Publications

Selected publications

2019

Kelmer Sacramento E*., Kirkpatrick J.M.*, Mazzetto M.*, Di Sanzo S., Caterino C., Sanguanini M., Papaevgeniou N., Lefaki M., Childs D., Bagnoli S., Terzibasi Tozzini E., Bartolome A., Romanov N., Baumgart M., Huber W., Chondrogianni N., Vendruscolo M., Cellerino A. #, and Ori A.#, (2019). Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation, bioRxiv, p. 577478.

Muntel J.*, Kirkpatrick J.*, Bruderer R., Huang T., Vitek O., Ori A.#, and Reiter L.#. (2019) Comparison of Protein Quantification in a Complex Background by DIA and TMT Workflows with Fixed Instrument Time. J. Proteome Res., 18, 1340–1351.

PDF        Research highlight (Genome Web)

2018

Wyant G.*, Abu-Remaileh M.*, Frenkel E., Laqtom N., Dharamdasani V., Heinze I., Ori A.#, and Sabatini D.M.# (2018). NUFIP1 is a ribosome receptor for starvation-induced ribophagy. Science 360, 751-758.

PDF        Research highlight (Mol Cell)    Research highlight (Science)

Parca L., Beck M., Bork P., and Ori A. (2018) Quantifying compartment‐associated variations of protein abundance in proteomics data. Mol. Syst. Biol. 14, e8131.

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Heinze I.*, Bens M.*, Calzia E.*, Holtze S., Dakhovnik O., Sahm A., Kirkpatrick J.M., Szafranski K., Romanov N., Sama S.N., Holzer K., Singer S., Ermolaeva M., Platzer M.#, Hildebrandt T.#, and Ori A.# (2018). Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging. BMC Biol. 16, 1–18.

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Buczak, K.*, Ori, A.*, Kirkpatrick, J.M., Holzer, K., Dauch, D., Roessler, S., Endris, V., Lasitschka, F., Parca, L., Schmidt, A., Zender, L., Schirmacher, P., Krijgsveld, J., Singer, S.#, and Beck, M.# (2018). Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC). Mol. Cell. Proteomics 17, 810–825.

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Ermolaeva, M.#, Neri, F.#, Ori, A.#, and Rudolph, K.L.# (2018). Cellular and epigenetic drivers of stem cell ageing. Nat. Rev. Mol. Cell Biol. 19, 1–17.

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2017

Mackmull, M.-T., Klaus, B, Heinze, I, Chokkalingam, M, Beyer, A, Russel, R. B., Ori, A.#, and Beck, M.# (2017). Landscape of nuclear transport receptor cargo specificity. Mol. Syst. Biol. 13, 962.

PDF    Research highlight (Cell Systems)

Cellerino, A.#, and Ori, A.# (2017). What have we learned on aging from omics studies? Semin. Cell Dev. Biol. 70, 177–189.

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2016

Ori, A.*, Iskar, M.*, Buczak, K., Kastritis, P., Parca, L., Andrés-Pons, A., Singer, S., Bork, P., and Beck, M. (2016). Spatiotemporal variation of mammalian protein complex stoichiometries. Genome Biol. 17, 47.

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2015

Ori, A.*, Toyama, B.H.*, Harris, M.S., Bock, T., Iskar, M., Bork, P., Ingolia, N.T., Hetzer, M.W., and Beck, M. (2015). Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats. Cell Syst. 1, 224–237.

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Mackmull, M.-T., Iskar, M., Parca, L., Singer, S., Bork, P., Ori, A.#, and Beck, M.# (2015). Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). Mol. Cell. Proteomics 14, 1350–1360.

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Poli, M.*, Ori, A.*, Child, T., Jaroudi, S., Spath, K., Beck, M., and Wells, D. (2015). Characterization and quantification of proteins secreted by single human embryos prior to implantation. EMBO Mol. Med. 7, 1465–1479.

PDF      Reproomics (our startup)

2013

Ori, A., Banterle, N., Iskar, M., Andrés-Pons, A., Escher, C., Khanh Bui, H., Sparks, L., Solis-Mezarino, V., Rinner, O., Bork, P., Lemke, E. and Beck, M. (2013). Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines. Mol. Syst. Biol. 9, 648.

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Complete list of publications